The migrant cells in allotransplants of heart, kidney and skin. II. Monocyte-macrophage activity.

  • W. J. Dempster
  • Published 1977 in British journal of experimental pathology
Within a few hours of transplantation the cells of the mononuclear phagocyte system migrate into the interstitial tissues of the organ. The cells arrive on the vascular endothelium of the allotransplanted organ either as macrophages or as monocytes but on entering the interstitial tissues they begin to enlarge, differentiate and undergo active pinocytosis… CONTINUE READING