The microstructural correlates of T1 in white matter.

  title={The microstructural correlates of T1 in white matter.},
  author={Kevin D. Harkins and Junzhong Xu and Adrienne N. Dula and Ke Li and William M. Valentine and Daniel F. Gochberg and John C. Gore and Mark D. Does},
  journal={Magnetic resonance in medicine},
  volume={75 3},
PURPOSE Several studies have shown strong correlations between myelin content and T1 within the brain, and have even suggested that T1 can be used to estimate myelin content. However, other micro-anatomical features such as compartment size are known to affect longitudinal relaxation rates, similar to compartment size effects in porous media. METHODS T1 measurements were compared with measured or otherwise published axon size measurements in white matter tracts of the rat spinal cord, rat… CONTINUE READING

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