The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model.

@article{Baer2003TheME,
  title={The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model.},
  author={Anthony E Baer and Tod A. Laursen and Farshid Guilak and Lori A. Setton},
  journal={Journal of biomechanical engineering},
  year={2003},
  volume={125 1},
  pages={1-11}
}
Cellular response to mechanical loading varies between the anatomic zones of the intervertebral disc. This difference may be related to differences in the structure and mechanics of both cells and extracellular matrix, which are expected to cause differences in the physical stimuli (such as pressure, stress, and strain) in the cellular micromechanical environment. In this study, a finite element model was developed that was capable of describing the cell micromechanical environment in the… CONTINUE READING

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