The microenvironment created by grafting rostral half-somites is mitogenic for neural crest cells.

@article{Goldstein1990TheMC,
  title={The microenvironment created by grafting rostral half-somites is mitogenic for neural crest cells.},
  author={Ronald S Goldstein and M. A. Teillet and Chaya Kalcheim},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 12},
  pages={4476-80}
}
Chicken embryo neural crest cells that migrate into a paraxial mesoderm constructed of multiple rostral half-somites from quail embryos form unsegmented "polyganglia," instead of distinct dorsal root ganglia (DRG). We report here that the environment that is created by grafting rostral somitic (RS) moieties not only is permissive for neural crest cell migration and consequent DRG formation but also is mitogenic for the DRG precursor cells. On embryonic day 3.5 (E3.5), 1 day after surgery, there… CONTINUE READING
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