The microbiome in early life: implications for health outcomes

@article{Tamburini2016TheMI,
  title={The microbiome in early life: implications for health outcomes},
  author={Sabrina Tamburini and Nan Shen and Han Wu and Jose C. Clemente},
  journal={Nature Medicine},
  year={2016},
  volume={22},
  pages={713-722}
}
Recent studies have characterized how host genetics, prenatal environment and delivery mode can shape the newborn microbiome at birth. Following this, postnatal factors, such as antibiotic treatment, diet or environmental exposure, further modulate the development of the infant's microbiome and immune system, and exposure to a variety of microbial organisms during early life has long been hypothesized to exert a protective effect in the newborn. Furthermore, epidemiological studies have shown… CONTINUE READING

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Normalizing the environment recapitulates adult human immune traits in laboratory mice

L. K. Beura
Nature • 2016

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