The microbiological transformation of 7alpha-hydroxy-ent-kaur-16-ene derivatives by Gibberella fujikuroi.

@article{Fraga2007TheMT,
  title={The microbiological transformation of 7alpha-hydroxy-ent-kaur-16-ene derivatives by Gibberella fujikuroi.},
  author={Braulio M. Fraga and Carlo Bressa and Pedro Gonz{\'a}lez and Ricardo Guillermo and Melchor G. Hern{\'a}ndez and Sergio Su{\'a}rez},
  journal={Phytochemistry},
  year={2007},
  volume={68 11},
  pages={
          1557-63
        }
}
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12 Citations
Highly Influential Citations
1
Background Citations
3
Methods Citations
2

12 Citations

Microbiological transformation of two 15α-hydroxy-ent-kaur-9(11),16-diene derivatives by the fungus Fusarium fujikuroi.
Biotransformation of 7alpha-hydroxy- and 7-oxo-ent-atis-16-ene derivatives by the fungus Gibberella fujikuroi.
New alkamide and ent-kaurane diterpenoid derivatives from Senecio erechtitoides (Asteraceae)
Microbial Transformation of the Diterpene 7-epi-Foliol by Fusarium fujikuroi
TLDR
The biotransformation of other 7α- or 7β-hydroxy derivatives had led to the oxidation of C-19, which is a main step in the biosynthesis of gibberellins and kaurenolides, but the presence of the 3a-hydroxyl impedes that oxidation.
Regio- and stereo-selective hydroxylations of ingenane diterpenoids by Mortierella ramanniana and Gibberella fujikuroi.
New stereoisomeric derivatives of jasmonic acid generated by biotransformation with the fungus Gibberella fujikuroi affect the viability of human cancer cells
TLDR
This work shows for the by first time the production of hydroxylated derivatives of JA by biotransformation and suggests that it, as other jasmonate compounds, is able to trigger apoptotic death in cancer cells.
Biotransformation of Di- and Triterpenoids, Steroids, and Miscellaneous Synthetic Substrates
The Remarkable Structural Diversity Achieved in ent-Kaurane Diterpenes by Fungal Biotransformations
TLDR
In this review, selected examples the wonderful chemical diversity produced by fungi in kaurane diterpenes is presented, which includes mainly hydroxylation of nearly all carbon atoms of the kurane molecule, many of them carried out stereoselectively, as well as ring rearrangements, among other chemical modifications.
Exploiting a Step in Diterpenoid Biosynthesis by the Fungus Fusarium Fujikuroi
The scope of the microbiological transformation of ent-kaurenoid diterpenes by the fungus Fusarium (Gibberella) fujikuroi which utilise the ent-kaurene and ent-kauren-19-oic acid oxidases and the…
Isolation, chemical, and biotransformation routes of labdane-type diterpenes.
TLDR
This work focuses on the separation and chemical Manipulation of Sclareol and its derivatives, and their applications in agriculture, materials science, and materials engineering.
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References

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The microbiological transformation of some ent-7α,15β-dihydroxykaurene derivatives by Gibberella fujikuroi
Biotransformation of two ent-15β-hydroxy-kaur-16-ene derivatives by Gibberella fujikuroi
Biotransformation of 7-oxo-ent-kaur-16-ene derivatives by Gibberella fujikuroi
Studies in terpenoid biosynthesis. Part IX. The sequence of oxidation on ring B in kaurene–gibberellin biosynthesis
The formation of 7β-hydroxy-(–)-kaur-16-en-19-oic acid and its incorporation into gibberellic acid and the kauranoid metabolites of Gibberella fujikuroi are described. The results of incubation of…
Kaurenolides and fujenoic acids are side products of the gibberellin P450-1 monooxygenase in Gibberella fujikuroi.
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The microbiological transformation of epicandicandiol, ent-7α,18-dihydroxykaur-16-ene, by Gibberella fujikuroi
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TLDR
The main difference observed in both feedings, resulting from the spatial change in the orientation of the 7-hydroxyl, was the formation of a 3alpha- and a 9beta-Hydroxylated derivative.
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