The microRNA (miRNA): overview of the RNA genes that modulate gene function.

  title={The microRNA (miRNA): overview of the RNA genes that modulate gene function.},
  author={S H Ying and Donald C. D. Chang and S L Lin},
  journal={Molecular biotechnology},
  volume={38 3},
MicroRNAs (miRNAs), widely distributed, small regulatory RNA genes, target both messenger RNA (mRNA) degradation and suppression of protein translation based on sequence complementarity between the miRNA and its targeted mRNA. Different names have been used to describe various types of miRNA. During evolution, RNA retroviruses or transgenes invaded the eukaryotic genome and inserted in the non-coding regions of DNA, conceivably acting as transposon-like jumping genes, providing defense from… CONTINUE READING

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