The methylproteome and the intracellular methylation network.

  title={The methylproteome and the intracellular methylation network.},
  author={Melissa A. Erce and Chi Nam Ignatius Pang and Gene Hart-Smith and Marc R. Wilkins},
  volume={12 4-5},
Since its discovery more than 50 years ago, post-translational modification (PTM) of proteins via methylation has grown in prominence, its involvement having been recognised in a number of central processes in the cell. Of these, the best characterised is its role in the epigenetic code. However, there is increasing evidence that its role extends far beyond this and we propose that it is a key regulator in interactome dynamics. In this review, we focus on the role of methylation in regulating… CONTINUE READING
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