The methylotrophic yeast Hansenula polymorpha: a versatile cell factory.

@article{vanDijk2000TheMY,
  title={The methylotrophic yeast Hansenula polymorpha: a versatile cell factory.},
  author={R vanDijk and Faber and Kiel and Veenhuis and I vanderKlei},
  journal={Enzyme and microbial technology},
  year={2000},
  volume={26 9-10},
  pages={
          793-800
        }
}
The development of heterologous overexpression systems for soluble proteins has greatly advanced the study of the structure/function relationships of these proteins and their biotechnological and pharmaceutical applications. In this paper we present an overview on several aspects of the use of the methylotrophic yeast Hansenula polymorpha as a host for heterologous gene expression. H. polymorpha has been successfully exploited as a cell factory for the large-scale production of such components… CONTINUE READING

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