The methylated component of the Neurospora crassa genome

@article{Selker2003TheMC,
  title={The methylated component of the Neurospora crassa genome},
  author={E. Selker and Nikolaos A. Tountas and S. Cross and B. Margolin and Jonathan G. Murphy and A. Bird and M. Freitag},
  journal={Nature},
  year={2003},
  volume={422},
  pages={893-897}
}
Cytosine methylation is common, but not ubiquitous, in eukaryotes. Mammals and the fungus Neurospora crassa have about 2–3% of cytosines methylated. In mammals, methylation is almost exclusively in the under-represented CpG dinucleotides, and most CpGs are methylated whereas in Neurospora, methylation is not preferentially in CpG dinucleotides and the bulk of the genome is unmethylated. DNA methylation is essential in mammals but is dispensable in Neurospora, making this simple eukaryote a… Expand
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