The methyl-branched fortifications of Mycobacterium tuberculosis.

  title={The methyl-branched fortifications of Mycobacterium tuberculosis.},
  author={David E. Minnikin and Laurent Kremer and Lynn George Dover and Gurdyal S Besra},
  journal={Chemistry & biology},
  volume={9 5},
Mycobacterium tuberculosis continues to be the predominant global infectious agent, annually killing over three million people. Recommended drug regimens have the potential to control tuberculosis, but lack of adherence to such regimens has resulted in the emergence of resistant strains. Mycobacterium tuberculosis has an unusual cell envelope, rich in unique long-chain lipids, that provides a very hydrophobic barrier to antibiotic access. Such lipids, however, can be drug targets, as… CONTINUE READING

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