Corpus ID: 90597066

The methods and compositions for increasing the iduronic acid 2-sulfatase activity in Cns

@inproceedings{2010TheMA,
  title={The methods and compositions for increasing the iduronic acid 2-sulfatase activity in Cns},
  author={ウィリアム・エム・パードリッジ and ルーベン・ジェイ・ボアド},
  year={2010}
}
This application provides methods and compositions for treating a subject suffering from iduronic acid 2-sulfatase deficiency in CNS. The method comprises the systemic administration of bifunctional fusion antibody comprising an antibody and iduronic acid 2-sulfatase through the blood brain barrier (BBB).