The metabolism or atropine in man
@article{Meer1986TheMO, title={The metabolism or atropine in man}, author={M. J. Meer and Hans K. L. Hundt and F. Otto M{\"u}ller}, journal={Journal of Pharmacy and Pharmacology}, year={1986}, volume={38} }
A metabolic pattern of atropine in man, based on the detection of radiolabelled products in urine by high performance liquid chromatography after administration of [3H]atropine sulphate to a normal volunteer is proposed. Noratropine (24%), atropine‐N‐oxide (equatorial isomer) (15%), tropine (2%) and tropic acid (3%) appear to be the major metabolites, while 50% of the administered dose is excreted as apparently unchanged atropine. No conjugates were detectable. Evidence that atropine is present…
18 Citations
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