The metabolism of pyruvate in the tricarboxylic acid cycle of developing mammalian liver.


Previous work has indicated that much of the biochemical maturation of the mammalian liver takes place around the time of birth (l-6). In the present study of this critical period, we have investigated the mode of pyruvate utilization in the tricarboxylic acid cycle. Pyruvate enters the tricarboxylic acid cycle in two ways, as acetyl coenzyme A and as a… (More)


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