The metabolism of methylsulfinylalkyl- and methylthioalkyl-glucosinolates by a selection of human gut bacteria.

@article{LuangIn2014TheMO,
  title={The metabolism of methylsulfinylalkyl- and methylthioalkyl-glucosinolates by a selection of human gut bacteria.},
  author={Vijitra Luang-In and Arjan Narbad and Carmen Nueno-Palop and Richard Mithen and Mark H. Bennett and John Trevor Rossiter},
  journal={Molecular nutrition & food research},
  year={2014},
  volume={58 4},
  pages={875-83}
}
SCOPE Certain myrosinase-positive human gut bacteria can metabolize glucosinolates (GSLs) to produce isothiocyanates (ITC) as chemopreventive agents. We investigated glucoerucin, glucoiberin, and glucoraphanin (present in broccoli) metabolism by human gut strains. METHODS AND RESULTS All tested bacteria metabolized glucoerucin to completion within 16 h to erucin and erucin nitrile (NIT). Lactobacillus agilis R16 metabolized only 10% of glucoiberin and glucoraphanin with no detectable products… CONTINUE READING
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