The metabolism of anserine and carnosine in normal and vitamin E-deficient rabbits.

  title={The metabolism of anserine and carnosine in normal and vitamin E-deficient rabbits.},
  author={I R McManus},
  journal={Journal of Biological Chemistry},
  • I. McManus
  • Published 1 May 1960
  • Chemistry
  • Journal of Biological Chemistry
Among the alterations observed in the nitrogenous constituents of skeletal muscle of severely vitamin E-deficient rabbits is a decrease in the concentrations of carnosine and anserine (1, 2). The experiments of Razina (3) on the synthesis of carnosine in hepatectomized and nephrectomized rats implicate skeletal muscle as a major site of their synthesis. This site is also indicated by studies on the synthesis in vitro of anserine and carnosine from the constituent amino acids by carnosine… Expand

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