The metabolism of 3,7-dimethyl-2,6-octadienal (citral) in rat hepatic mitochondrial and cytosolic fractions. Interactions with aldehyde and alcohol dehydrogenases.

Abstract

Citral (3,7-dimethyl-2,6-octadienal), a flavoring and fragrance agent, is associated with a variety of biochemical and toxicological effects. Reports of the in vivo metabolism of citral suggest that a primary route of metabolism is conversion to the corresponding acid species presumably by aldehyde dehydrogenases (ALDH). In the present study, hepatic… (More)

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@article{Boyer1991TheMO, title={The metabolism of 3,7-dimethyl-2,6-octadienal (citral) in rat hepatic mitochondrial and cytosolic fractions. Interactions with aldehyde and alcohol dehydrogenases.}, author={C{\'e}lia Boyer and Dennis R. Petersen}, journal={Drug metabolism and disposition: the biological fate of chemicals}, year={1991}, volume={19 1}, pages={81-6} }