The metabolic syndrome and smoking in relation to hypogonadism in middle-aged men: a prospective cohort study.

@article{Laaksonen2005TheMS,
  title={The metabolic syndrome and smoking in relation to hypogonadism in middle-aged men: a prospective cohort study.},
  author={David E. Laaksonen and Leo Niskanen and Kari Punnonen and Kristiina Nyyss{\"o}nen and Tomi-Pekka Tuomainen and V P Valkonen and Jukka Salonen},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2005},
  volume={90 2},
  pages={
          712-9
        }
}
In men, hypoandrogenism is associated with features of the metabolic syndrome. It is not known whether men with the metabolic syndrome are at a higher risk of developing hypogonadism. We therefore assessed whether the metabolic syndrome predicts development of hypogonadism 11 yr later in 651 middle-aged Finnish men participating in a population-based cohort study. Men with the metabolic syndrome at baseline as defined by the World Health Organization (n = 114, 20%) had a 2.6-fold increased risk… CONTINUE READING
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