The metabolic syndrome and signal transduction of gene expression.

@article{Rupp1991TheMS,
  title={The metabolic syndrome and signal transduction of gene expression.},
  author={Hans. Rupp},
  journal={Basic research in cardiology},
  year={1991},
  volume={86 Suppl 3},
  pages={
          65-81
        }
}
Epidemiological studies have clearly shown that the so-called metabolic syndrome which is linked to insulin resistance and a reduced glucose utilization of muscle represents an important risk factor for cardiovascular disease. However, only little is known of the intracellular consequences of insulin resistance. An important feature of an altered substrate utilization is related to signal transduction of gene expression. For the example of myosin heavy chain expression, it is shown that… CONTINUE READING
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