The metabolic enzyme CTP synthase forms cytoskeletal filaments

@inproceedings{IngersonMahar2010TheME,
  title={The metabolic enzyme CTP synthase forms cytoskeletal filaments},
  author={Michael J. Ingerson-Mahar and Ariane Briegel and John N. Werner and Grant J. Jensen and Zemer Gitai},
  booktitle={Nature Cell Biology},
  year={2010}
}
Filament-forming cytoskeletal proteins are essential for the structure and organization of all cells. Bacterial homologues of the major eukaryotic cytoskeletal families have now been discovered, but studies suggest that yet more remain to be identified. We demonstrate that the metabolic enzyme CTP synthase (CtpS) forms filaments in Caulobacter crescentus. CtpS is bifunctional, as the filaments it forms regulate the curvature of C. crescentus cells independently of its catalytic function. The… CONTINUE READING
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