The metabolic cost of neural information

@article{Laughlin1998TheMC,
  title={The metabolic cost of neural information},
  author={S. Laughlin and Rob R. de Ruyter van Steveninck and J. Anderson},
  journal={Nature Neuroscience},
  year={1998},
  volume={1},
  pages={36-41}
}
  • S. Laughlin, Rob R. de Ruyter van Steveninck, J. Anderson
  • Published 1998
  • Biology, Medicine
  • Nature Neuroscience
  • We derive experimentally based estimates of the energy used by neural mechanisms to code known quantities of information. Biophysical measurements from cells in the blowfly retina yield estimates of the ATP required to generate graded (analog) electrical signals that transmit known amounts of information. Energy consumption is several orders of magnitude greater than the thermodynamic minimum. It costs 104 ATP molecules to transmit a bit at a chemical synapse, and 106 - 107 ATP for graded… CONTINUE READING

    Figures and Topics from this paper.

    Fly Photoreceptors Demonstrate Energy-Information Trade-Offs in Neural Coding
    • 224
    • PDF
    Efficient information transfer by Poisson neurons.
    • 4
    • PDF
    Information and Efficiency in the Nervous System—A Synthesis
    • 126
    • PDF

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 48 REFERENCES
    Energy Efficient Neural Codes
    • 386
    Analog Versus Digital: Extrapolating from Electronics to Neurobiology
    • 399
    • PDF