The meningococcal PilT protein is required for induction of intimate attachment to epithelial cells following pilus-mediated adhesion.

Abstract

The ability of Neisseria meningitidis (MC) to interact with cellular barriers is essential to its pathogenesis. With epithelial cells, this process has been modeled in two steps. The initial stage of localized adherence is mediated by bacterial pili. After this phase, MC disperse and lose piliation, thus leading to a diffuse adherence. At this stage… (More)

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@article{Pujol1999TheMP, title={The meningococcal PilT protein is required for induction of intimate attachment to epithelial cells following pilus-mediated adhesion.}, author={Clara Pujol and Emmanuel Eug{\`e}ne and Michael Marceau and Xavier Nassif}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1999}, volume={96 7}, pages={4017-22} }