The membrane transporters regulating epithelial NaCl secretion

  title={The membrane transporters regulating epithelial NaCl secretion},
  author={Rainer Greger},
  journal={Pfl{\"u}gers Archiv - European Journal of Physiology},
Ten years ago, the basic principles operating in one specific, albeit non-mammalian, exocrine gland, the rectal gland of Squalus acanthias, were described in detail. The concept emerging from these studies appeared applicable to almost any other exocrine gland, because it involved membrane transporters which are also present in mammalian epithelial cells. Meanwhile, it has become clear that the mechanisms of NaCl secretion are diverse: the mechanisms of NaCl uptake; the ion channels involved… CONTINUE READING