The membrane-integrated transcriptional activator CadC of Escherichia coli senses lysine indirectly via the interaction with the lysine permease LysP.

@article{Tetsch2008TheMT,
  title={The membrane-integrated transcriptional activator CadC of Escherichia coli senses lysine indirectly via the interaction with the lysine permease LysP.},
  author={Larissa Tetsch and Christiane M Koller and Ina Haneburger and Kirsten Jung},
  journal={Molecular microbiology},
  year={2008},
  volume={67 3},
  pages={570-83}
}
In an acidic (pH 5.8) and lysine-rich environment Escherichia coli induces expression of the cadBA operon which encodes CadA, catalysing the decarboxylation of lysine to cadaverine, and CadB, the lysine/cadaverine antiporter. cadBA expression is dependent on CadC, a membrane-integrated transcriptional activator which belongs to the ToxR-like protein family… CONTINUE READING