The membrane and lipids as integral participants in signal transduction: lipid signal transduction for the non-lipid biochemist.
@article{Eyster2007TheMA, title={The membrane and lipids as integral participants in signal transduction: lipid signal transduction for the non-lipid biochemist.}, author={K. Eyster}, journal={Advances in physiology education}, year={2007}, volume={31 1}, pages={ 5-16 } }
Reviews of signal transduction have often focused on the cascades of protein kinases and protein phosphatases and their cytoplasmic substrates that become activated in response to extracellular signals. Lipids, lipid kinases, and lipid phosphatases have not received the same amount of attention as proteins in studies of signal transduction. However, lipids serve a variety of roles in signal transduction. They act as ligands that activate signal transduction pathways as well as mediators of… CONTINUE READING
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