The melanocyte differentiation pathway in spitz nevi.

  title={The melanocyte differentiation pathway in spitz nevi.},
  author={Stewart F Cramer},
  journal={The American Journal of dermatopathology},
  volume={20 6},
The nature of Spitz nevi is poorly understood, and their distinction from malignant melanoma can be difficult. Although there is general agreement on the diagnostic criteria, experts continue to have some differences, and controversial cases are not rare. A major obstacle to progress in this area is the lack of basic knowledge about melanocyte differentiation in Spitz nevi, as compared with ordinary nevi and malignant melanomas. Based on the hypothesis that normal melanocytes may have a… CONTINUE READING
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