The mechanobiological theory: a unifying hypothesis on the pathogenesis of moyamoya disease based on a systematic review.

@article{Sudhir2021TheMT,
  title={The mechanobiological theory: a unifying hypothesis on the pathogenesis of moyamoya disease based on a systematic review.},
  author={Bhanu Jayanand Sudhir and Arun Gowda Keelara and Easwer Harihara Venkat and Ken Kazumata and Ananthalakshmy Sundararaman},
  journal={Neurosurgical focus},
  year={2021},
  volume={51 3},
  pages={
          E6
        }
}
OBJECTIVE Moyamoya angiopathy (MMA) affects the distal internal carotid artery and is designated as moyamoya disease (MMD) when predisposing conditions are absent, or moyamoya syndrome (MMS) when it occurs secondary to other causes. The authors aimed to investigate the reason for this anatomical site predilection of MMA. There is compelling evidence to suggest that MMA is a phenomenon that occurs due to stereotyped mechanobiological processes. Literature regarding MMD and MMS was systematically…