The mechanistic role of chemically diverse metal ions in the induction of autophagy.

@article{Sahni2017TheMR,
  title={The mechanistic role of chemically diverse metal ions in the induction of autophagy.},
  author={Sumit Sahni and Dong-Hun Bae and Patric J. Jansson and Des. R. Richardson},
  journal={Pharmacological research},
  year={2017},
  volume={119},
  pages={118-127}
}
Autophagy is an evolutionary conserved cellular catabolic degradation process in response to stress which involves lysosomal degradation of unnecessary or damaged organelles and misfolded proteins. This is primarily a pro-survival pathway providing the cell with essential nutrients during stressful conditions. There are number of essential metal ions, which are required for normal physiological functioning of cells. Studies have shown that autophagy can be regulated by cellular metal ion… CONTINUE READING

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