The mechanisms of muscle hypertrophy and their application to resistance training.

@article{Schoenfeld2010TheMO,
  title={The mechanisms of muscle hypertrophy and their application to resistance training.},
  author={Brad Jon Schoenfeld},
  journal={Journal of strength and conditioning research},
  year={2010},
  volume={24 10},
  pages={
          2857-72
        }
}
  • B. Schoenfeld
  • Published 1 October 2010
  • Education
  • Journal of strength and conditioning research
The quest to increase lean body mass is widely pursued by those who lift weights. Research is lacking, however, as to the best approach for maximizing exercise-induced muscle growth. Bodybuilders generally train with moderate loads and fairly short rest intervals that induce high amounts of metabolic stress. Powerlifters, on the other hand, routinely train with high-intensity loads and lengthy rest periods between sets. Although both groups are known to display impressive muscularity, it is not… 
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752 Citations
Highly Influential Citations
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Background Citations
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Methods Citations
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Results Citations
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752 Citations

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Maximizing Muscle Hypertrophy: A Systematic Review of Advanced Resistance Training Techniques and Methods

It is difficult to provide specific guidelines for volume, intensity of effort, and frequency of previously mentioned RT techniques and methods, however, well-trained athletes may integrate advanced RT Techniques and methods into their routines as an additional stimulus to break through plateaus and to prevent training monotony.

Are resistance training systems necessary to avoid a stagnation and maximize the gains muscle strength and hypertrophy?

Acute and Chronic Testosterone Response to Blood Flow Restricted Exercise

It is suggested that systemic increases of endogenous testosterone are not necessary for muscular hypertrophy to occur, but definitive conclusions cannot be made without a more thorough analysis of responses of androgen receptor density following blood flow restricted exercise.

Resistance Training Recommendations to Maximize Muscle Hypertrophy in an Athletic Population: Position Stand of the IUSCA

Hypertrophy can be operationally defined as an increase in the axial cross-sectional area of a muscle fiber or whole muscle, and is due to increases in the size of pre-existing muscle fibers.…

Eccentric Resistance Training and Muscle Hypertrophy

The aim of this brief review is to point out the benefits of eccentric training programs, highlighting its effects on muscle hypertrophy, and to indicate the difficulties that can rise when employing such a model.

Resistance training variables on muscle hypertrophy: a systematic review

The PEDro scale was used to analyse the quality of the selected articles and it was concluded that the variables intensity and volume must be carefully analysed in a training program.

Is There a Minimum Intensity Threshold for Resistance Training-Induced Hypertrophic Adaptations?

Current research indicates that low-load exercise can indeed promote increases in muscle growth in untrained subjects, and that these gains may be functionally, metabolically, and/or aesthetically meaningful, whether hypertrophic adaptations can equal that achieved with higher intensity resistance exercise.

EVIDENCE!BASED RESISTANCE TRAINING RECOMMENDATIONS FOR MUSCULAR HYPERTROPHY

Evidence supports that persons should train to the highest intensity of effort, thus recruiting as many motor units and muscle fibres as possible, self-selecting a load and repetition range, and performing single sets for each exercise, and evidence suggests that short periods of detraining in trained persons might stimulate greater hypertrophy upon return to training.

Skeletal Muscle Hypertrophy, Maximal Strength, and Rate of Force Development: Effects of Resistance Training Loading Strategy

The purpose of the current study was to compare RISR to RM programs on measures of muscle fiber hypertrophy, maximal strength, and rate of force development (RFD) in well-trained lifters.
...

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