The mechanisms of hydrolysis of glycosides and their revelance to enzyme-catalysed reactions

@article{Vernon1967TheMO,
  title={The mechanisms of hydrolysis of glycosides and their revelance to enzyme-catalysed reactions},
  author={C. Vernon},
  journal={Proceedings of the Royal Society of London. Series B. Biological Sciences},
  year={1967},
  volume={167},
  pages={389 - 401}
}
  • C. Vernon
  • Published 1967
  • Medicine
  • Proceedings of the Royal Society of London. Series B. Biological Sciences
  • Glycoside hydrolysis can be formally represented by (I). where the group OR (R is alkyl, aryl or a carbohydrate) is displaced from the C1 or C2 atom of an aldose or ketose sugar (or sugar derivative) respectively; the ring system being either five- or six-membered. Like the analogous hydrolysis of acetals, glycoside hydrolysis shows specific catalysis by hydrogen ions and, except where R is an aryl residue, base catalysis is absent. A number of enzymes* catalysing the hydrolysis of particular… CONTINUE READING
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