The mechanisms of cytotoxicity of urethane dimethacrylate to Chinese hamster ovary cells.

@article{Chang2010TheMO,
  title={The mechanisms of cytotoxicity of urethane dimethacrylate to Chinese hamster ovary cells.},
  author={Hsiao-Hua Chang and M X Chang and Li-Deh Lin and Jang-Jaer Lee and Tong-Mei Wang and Chun-Hsun Huang and Ting-Ting Yang and Hsueh-Jen Lin and J G Jeng},
  journal={Biomaterials},
  year={2010},
  volume={31 27},
  pages={6917-25}
}
Monomers released from resin-containing products may cause various adverse effects. Urethane dimethacrylate (UDMA) is a principal resin monomer and also a major component released from various dental resin materials. Thus the toxic effects and mechanisms should be elucidated for improving of its safety use. Here we investigated the effects of UDMA on the growth, cell cycle progression, reactive oxygen species (ROS) production and glutathione (GSH) alteration in CHO-K1 cells, and the preventive… CONTINUE READING
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N - acetyl cysteine directed detoxi fi cation of 2hydroxyethyl methacrylate by adduct formation

  • G Nocca, V D’Anto, C Desiderio, DV Rossetti, R Valletta, AM Baguala
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