The mechanism of the remodeling of high density lipoproteins by phospholipid transfer protein.

@article{Settasatian2001TheMO,
  title={The mechanism of the remodeling of high density lipoproteins by phospholipid transfer protein.},
  author={Nongnuch Settasatian and Myngan Duong and Linda K. Curtiss and Christian P Ehnholm and Matti S Jauhiainen and Jarkko Huuskonen and Kerry-Anne Rye},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 29},
  pages={26898-905}
}
Phospholipid transfer protein (PLTP) remodels high density lipoproteins (HDL) into large and small particles. It also mediates the dissociation of lipid-poor or lipid-free apolipoprotein A-I (apoA-I) from HDL. Remodeling is enhanced markedly in triglyceride (TG)-enriched HDL (Rye, K.-A., Jauhiainen, M., Barter, P. J., and Ehnholm. C. (1998) J. Lipid. Res. 39, 613-622). This study defines the mechanism of the remodeling of HDL by PLTP and determines why it is enhanced in TG-enriched HDL… CONTINUE READING

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