The mechanism of synthesis of amino acids by electric discharges.

@article{Miller1957TheMO,
  title={The mechanism of synthesis of amino acids by electric discharges.},
  author={S. Miller},
  journal={Biochimica et biophysica acta},
  year={1957},
  volume={23 3},
  pages={
          480-9
        }
}
  • S. Miller
  • Published 1957
  • Chemistry, Medicine
  • Biochimica et biophysica acta
The mechanism of the electric discharge synthesis of amino and hydroxy acids from CH4, NH3, H2O, and H2 was investigated. Hydrogen cyanide and aldehydes, which are produced in good yield by the spark discharge, react to form amino and hydroxynitriles (Strecker synthesis). The rate of hydrolysis of the aminonitriles formed from the products of the spark discharge is sufficient to account for the total yield of amino acids after a week's sparking. The β-alanine and succinic acid were probably… Expand
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