The mechanism of macrophage activation induced by Ca2+ ionophore.

@article{Onozaki1983TheMO,
  title={The mechanism of macrophage activation induced by Ca2+ ionophore.},
  author={Kikuo Onozaki and Tadaomi Takenawa and Yoshimi Homma and Tetsuya Hashimoto},
  journal={Cellular immunology},
  year={1983},
  volume={75 2},
  pages={242-54}
}
The mechanism of macrophage activation by Ca2+ ionophore was studied. Peritoneal exudate macrophages from normal guinea pigs exposed continuously to or pulse treated for 1 hr with the ionophore, A23187, were activated, manifesting increased glucose consumption and inhibition of migration. Highly purified macrophages were also activated as effectively as… CONTINUE READING