The mechanism of adenosylcobalamin-dependent rearrangements.

@article{Babior1988TheMO,
  title={The mechanism of adenosylcobalamin-dependent rearrangements.},
  author={Bernard M. Babior},
  journal={BioFactors},
  year={1988},
  volume={1 1},
  pages={21-6}
}
Adenosylcobalamin (AdoCbl)-dependent rearrangements are a group of reactions with no obvious precedents in organic chemistry. In every case, they are characterized by a mechanism in which a hydrogen atom on one carbon atom exchanges places with a group X on an adjacent carbon: (formula; see text) Much experimental work indicates that an AdoCbl rearrangement… CONTINUE READING