The mechanism of adenosylcobalamin-dependent rearrangements.

  title={The mechanism of adenosylcobalamin-dependent rearrangements.},
  author={Bernard M. Babior},
  volume={1 1},
Adenosylcobalamin (AdoCbl)-dependent rearrangements are a group of reactions with no obvious precedents in organic chemistry. In every case, they are characterized by a mechanism in which a hydrogen atom on one carbon atom exchanges places with a group X on an adjacent carbon: (formula; see text) Much experimental work indicates that an AdoCbl rearrangement… CONTINUE READING