The mechanism of activation of human natural killer cells by medullasin.

  • Yasumichi Aoki
  • Published 1986 in Japanese journal of cancer research : Gann


Medullasin, a serine protease in granulocytes, has been shown to stimulate human natural killer cell activity through its proteolytic activity, without interferon induction. The protease is considered to exert its effect directly on large granular lymphocytes, because firstly the extent of activation of natural killer cell activity by medullasin was the… (More)


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