The mechanism of action of thyroid hormones.

@article{Zhang2000TheMO,
  title={The mechanism of action of thyroid hormones.},
  author={Jun Zhang and Mitchell A Lazar},
  journal={Annual review of physiology},
  year={2000},
  volume={62},
  pages={439-66}
}
Thyroid hormone is essential for normal development, differentiation, and metabolic balance. Thyroid hormone action is mediated by multiple thyroid hormone receptor isoforms derived from two distinct genes. The thyroid hormone receptors belong to a nuclear receptor superfamily that also includes receptors for other small lipophilic hormones. Thyroid hormone receptors function by binding to specific thyroid hormone-responsive sequences in promoters of target genes and by regulating transcription… CONTINUE READING
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