The mechanism of action of lymphokines. VII. Modulation of the action of macrophage migration inhibitory factor by antioxidants and drugs affecting thromboxane synthesis.

@article{Jakubowski1983TheMO,
  title={The mechanism of action of lymphokines. VII. Modulation of the action of macrophage migration inhibitory factor by antioxidants and drugs affecting thromboxane synthesis.},
  author={Aniela Jakubowski and Edgar Pick},
  journal={Immunopharmacology},
  year={1983},
  volume={6 3},
  pages={215-29}
}
Guinea pig peritoneal exudate macrophages are active producers of oxygen radicals in response to membrane stimulation. We examined the involvement of oxygen radicals in the inhibition of macrophage migration caused by the lymphokine, macrophage migration inhibitory factor (MIF). It was found that the presence of scavengers of superoxide and hydrogen… CONTINUE READING