The mechanism of UVB irradiation induced-apoptosis in cataract

  title={The mechanism of UVB irradiation induced-apoptosis in cataract},
  author={Yinghong Ji and Lei Cai and Tianyu Zheng and Hongfei Ye and Xianfang Rong and Jun Rao and Yi Lu},
  journal={Molecular and Cellular Biochemistry},
Cataract is the most common eye disease that causes blindness in patients. Ultraviolet B (UVB) irradiation is considered an important factor leading to cataract by inducing apoptosis in human lens epithelial cells (HLECs), but the mechanism is currently unclear. In this study, we investigated HLECs under different intensities of UVB irradiation and different exposure time. The annexin V-FITC/propidium iodide staining results showed that UVB irradiation could efficiently lead to HLECs apoptosis… CONTINUE READING


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UVB-Induced Activation of PARP-1 in Cultured Human Lens Epithelial Cells (Doctoral dissertation, Oakland

  • DP Feldmann
  • Mol Cell Biochem
  • 2012
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