The mechanics of F-actin microenvironments depend on the chemistry of probing surfaces.

@article{McGrath2000TheMO,
  title={The mechanics of F-actin microenvironments depend on the chemistry of probing surfaces.},
  author={James L. McGrath and John H. Hartwig and Scot C. Kuo},
  journal={Biophysical journal},
  year={2000},
  volume={79 6},
  pages={3258-66}
}
To understand the microscopic mechanical properties of actin networks, we monitor the motion of embedded particles with controlled surface properties. The highly resolved Brownian motions of these particles reveal the viscoelastic character of the microenvironments around them. In both non-cross-linked and highly cross-linked actin networks, particles that bind F-actin report viscoelastic moduli comparable to those determined by macroscopic rheology experiments. By contrast, particles modified… CONTINUE READING