The measurement of immediate and persistent radiation-induced chromosome damage in rodent primary cells using premature chromosome condensation.

@article{Pantelias1985TheMO,
  title={The measurement of immediate and persistent radiation-induced chromosome damage in rodent primary cells using premature chromosome condensation.},
  author={Gabriel E. Pantelias and H. David Maillie},
  journal={Health physics},
  year={1985},
  volume={49 3},
  pages={
          425-33
        }
}
The chromosome damage observed in cultured peripheral blood lymphocytes at their metaphase is considered to be the most reliable basis for biological dosimetry. However, physical and biological factors such as irradiation conditions and chromosome repair could make difficult the interpretation of chromosome aberration yield in terms of absorbed dose. To establish correction factors to take into account partial body exposure, dose rate, and post-irradiation time requires in-vivo studies. Yet… CONTINUE READING
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