The matrix effects on kinetic rate constants of antibody-antigen interactions reflect solvent viscosity.

@article{Morgan1998TheME,
  title={The matrix effects on kinetic rate constants of antibody-antigen interactions reflect solvent viscosity.},
  author={Claire L. Morgan and David J. Newman and Jacky M. Burrin and Christopher P Price},
  journal={Journal of immunological methods},
  year={1998},
  volume={217 1-2},
  pages={51-60}
}
This study describes the influence of different matrices on two model antibody-antigen interactions; that between beta2microglobulin and anti beta2microglobulin, and that of rabbit anti mouse Fc fragment (RAMFc) with mouse IgG. The matrices investigated were; phosphate-buffered saline pH 7.4 containing 0.05% Tween 20 detergent, horse serum, a 50:50 mixture… CONTINUE READING