The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain.

@article{Loc1988TheMA,
  title={The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain.},
  author={P V Loc and Wolf H. Str{\"a}tling},
  journal={The EMBO journal},
  year={1988},
  volume={7 3},
  pages={655-64}
}
The matrix attachment regions of the chicken lysozyme domain were studied in an in vitro DNA binding assay by incubating oviduct nuclear matrices with labeled restriction fragments. A strong attachment region was localized between 11.1 and 8.85 kb upstream of the transcription start site and a weaker one between 1.3 and 5.0 kb downstream of the poly(A)+ addition site. Both attachment regions co-map with the previously established boundaries of the chromatin domain. The upstream matrix… CONTINUE READING

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