The mas oncogene encodes an angiotensin receptor

  title={The mas oncogene encodes an angiotensin receptor},
  author={Trevor R. Jackson and Leslie A. C. Blair and John Marshall and Michel Goedert and Michael R. Hanley},
The class of receptors coupled to GTP-binding proteins share a conserved structural motif which is described as a 'seven-transmembrane segment'1 following the prediction that these hydrophobic segments form membrane-spanning α-helices. Identified examples include the mammalian opsins2, α1-, α2-, β1- and β2-adrenergic receptors3, the muscarinic receptor family4,5, the 5-HT1C-receptor6, and the substance-K receptor7. In addition, two mammalian genes have been identified that code for predicted… CONTINUE READING


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Molecular Reviews in Cardiovascular Medicine

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Altered heart rate and blood pressure variability in mice lacking the Mas protooncogene.

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