The marsupial male: a role model for sexual development.

  title={The marsupial male: a role model for sexual development.},
  author={Marilyn B Renfree and Jenny L. Harry and Geoffrey Shaw},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  volume={350 1333},
Sexual differentiation in male marsupials has many similarities with that of eutherians. Marsupials have an XX-XY sex determining mechanism, and have a homologue of the testis-determining SRY gene on their Y-chromosome. However, the development pattern of SRY gene expression is different from the mouse in that it is expressed for a much longer period. SRY is expressed in a range of non-gonadal tissues in male pouch young and adults which is similar to the human pattern, and raises questions as… CONTINUE READING


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