The marker (X) syndrome: a cytogenetic and genetic analysis.

  title={The marker (X) syndrome: a cytogenetic and genetic analysis.},
  author={Stephanie L. Sherman and Newton E. Morton and Patricia A. Jacobs and Gillian Turner},
  journal={Annals of human genetics},
  volume={48 1},
The results of a cytogenetic and segregation analysis of 110 pedigrees of the mar (X) syndrome are reported. The cytogenetic study indicated an inverse relationship between IQ and the mar(X) frequency in females but not in males. A small but significant effect of age on mar(X) frequency was observed in both males and females, but in females it was restricted to those of normal intelligence, retarded females showing no significant effect. Classical segregation analysis was performed using the… CONTINUE READING
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