The marine medaka Oryzias melastigma--a potential marine fish model for innate immune study.

@article{Bo2011TheMM,
  title={The marine medaka Oryzias melastigma--a potential marine fish model for innate immune study.},
  author={Jun Bo and Ling Yan Cai and Jia-he Xu and Kejian Wang and Doris Wai-Ting Au},
  journal={Marine pollution bulletin},
  year={2011},
  volume={63 5-12},
  pages={267-76}
}
The objective of this study is to develop the marine medaka Oryzias melastigma as a potential marine fish model for innate immune and immunotoxicological studies. Hepcidin plays an important role in innate immune system. Two hepcidin genes (OM-hep1 and OM-hep2) were identified and characterized in the O. melastigma, which were highly conserved with other reported hepcidins. During embryogenesis, significant elevation of OM-hep1 and OM-hep2 transcripts were coincided with liver development in… CONTINUE READING