The many tales of a tail: carboxyl-terminal tail heterogeneity specializes histone H2A variants for defined chromatin function.

@article{Ausi2002TheMT,
  title={The many tales of a tail: carboxyl-terminal tail heterogeneity specializes histone H2A variants for defined chromatin function.},
  author={Juan Ausi{\'o} and D Wade Abbott},
  journal={Biochemistry},
  year={2002},
  volume={41 19},
  pages={5945-9}
}
For many years, histones were considered to be passive structural components of eukaryotic chromatin. Experimental evidence that has accumulated during the past few years indicates that in addition to their structural role, histones play a very important functional role and that they can operate as epigenetic markers. This notion has rekindled the interest in histone variants and their participation in the processes of chromatin activation and inactivation. Recent papers have focused their… CONTINUE READING

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