The many-state partition sum in DNA and RNA hybridization and its application to microarrays

Abstract

The assumption that DNA and RNA hybridization can be described by a two-state model, is unjustified for analysis of microarrays. It is expected that microarray analysis would benefit from a model which takes into account many different possible configurations. In this thesis, we present the tools developed to allow a many-state analysis of microarrays, and… (More)

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