The many paths to fear

@article{Gross2012TheMP,
  title={The many paths to fear},
  author={Cornelius T. Gross and Newton Sabino Canteras},
  journal={Nature Reviews Neuroscience},
  year={2012},
  volume={13},
  pages={651-658}
}
Fear is an emotion that has powerful effects on behaviour and physiology across animal species. It is accepted that the amygdala has a central role in processing fear. However, it is less widely appreciated that distinct amygdala outputs and downstream circuits are involved in different types of fear. Data show that fear of painful stimuli, predators and aggressive members of the same species are processed in independent neural circuits that involve the amygdala and downstream hypothalamic and… Expand

Paper Mentions

Interventional Clinical Trial
This study aims to specifically examine the in vivo electrophysiology and effects of direct stimulation of the human amygdala during conditioned and evoked fear. Investigators will also… Expand
ConditionsFear, Panic Disorder, PTSD
InterventionBehavioral, Device
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Mechanistic studies demonstrate that both regions can control the expression of fear and anxiety during sustained exposure to diffuse threat and compel a reconsideration of the central extended amygdala's contributions toFear and anxiety and its role in neuropsychiatric disease. Expand
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